Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity
نویسندگان
چکیده
منابع مشابه
Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity.
The hypothalamus is one of the most complex brain structures involved in homeostatic regulation. Defining cell composition and identifying cell-type-specific transcriptional features of the hypothalamus is essential for understanding its functions and related disorders. Here, we report single-cell RNA sequencing results of adult mouse hypothalamus, which defines 11 non-neuronal and 34 neuronal ...
متن کاملSingle-Cell RNA-Seq Reveals Melanoma Transcriptional Heterogeneity.
Single-cell analyses of 4,645 cells in multiple cell types reveal metastatic melanoma ecosystem.
متن کاملDetecting heterogeneity in single-cell RNA-Seq
21 Single-cell RNA-Sequencing (scRNA-Seq) is a cutting edge technology that enables the 22 understanding of biological processes at an unprecedentedly high resolution. However, 23 well suited bioinformatics tools to analyze the data generated from this new technology 24 are still lacking. Here we have investigated the performance of non-negative matrix 25 factorization (NMF) method to analyze a...
متن کاملSingle-cell RNA-Seq unveils tumor microenvironment
Single cell transcriptome analysis is a powerful tool for defining cell types or sub-populations within a heterogeneous bulk population. Tumor-associated microenvironment is a complex ecosystem consisting of numerous cell types that support tumor growth, angiogenesis, immune evasion, and metastasis. With the success of checkpoint inhibitors targeting the immune cell compartment, tumor microenvi...
متن کاملI-42: Origins and Differentiation of Somatic Progenitors of The Mammalian Gonad Revealed by Single Cell RNA-Seq
Background - MaterialsAndMethods N;Results N;Conclusion N;
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Reports
سال: 2017
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2017.03.004